A narrative review of proteolytic targeting chimeras (PROTACs): future perspective for prostate cancer therapy

Proteolysis-TArgeting Chimeras (PROTACs) technology, as a strategy to chemically knock down transcription factors at the protein levels, can hijack the ubiquitin-proteasome degradation system to initiate the intracellular ubiquitin-proteasome hydrolysis process to degrade proteins. In the past, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xuanrong, Shen, Haishan, Shao, Yi, Ma, Qianwang, Niu, Yuanjie, Shang, Zhiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947434/
https://www.ncbi.nlm.nih.gov/pubmed/33718095
http://dx.doi.org/10.21037/tau-20-1357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947434/
https://www.ncbi.nlm.nih.gov/pubmed/33718095
http://dx.doi.org/10.21037/tau-20-1357

Ejemplares similares