Cargando…
A narrative review of proteolytic targeting chimeras (PROTACs): future perspective for prostate cancer therapy
Proteolysis-TArgeting Chimeras (PROTACs) technology, as a strategy to chemically knock down transcription factors at the protein levels, can hijack the ubiquitin-proteasome degradation system to initiate the intracellular ubiquitin-proteasome hydrolysis process to degrade proteins. In the past, the...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
AME Publishing Company
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947434/ https://www.ncbi.nlm.nih.gov/pubmed/33718095 http://dx.doi.org/10.21037/tau-20-1357 |