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Exposure to Dengue Envelope Protein Domain III Induces Nlrp3 Inflammasome-Dependent Endothelial Dysfunction and Hemorrhage in Mice

Typically occurring during secondary dengue virus (DENV) infections, dengue hemorrhagic fever (DHF) causes abnormal immune responses, as well as endothelial vascular dysfunction, for which the responsible viral factor remains unclear. During peak viremia, the plasma levels of virion-associated envel...

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Detalles Bibliográficos
Autores principales: Lien, Te-Sheng, Sun, Der-Shan, Wu, Cheng-Yeu, Chang, Hsin-Hou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947687/
https://www.ncbi.nlm.nih.gov/pubmed/33717109
http://dx.doi.org/10.3389/fimmu.2021.617251