Cargando…

Natural Selection on the Phase-Separation Properties of FUS during 160 My of Mammalian Evolution

Protein phase separation can help explain the formation of many nonmembranous organelles. However, we know little about its ability to change in evolution. Here we studied the evolution of the mammalian RNA-binding protein Fused in Sarcoma (FUS), a protein whose prion-like domain (PLD) contributes t...

Descripción completa

Detalles Bibliográficos
Autores principales: Dasmeh, Pouria, Wagner, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947763/
https://www.ncbi.nlm.nih.gov/pubmed/33022038
http://dx.doi.org/10.1093/molbev/msaa258