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Natural Selection on the Phase-Separation Properties of FUS during 160 My of Mammalian Evolution
Protein phase separation can help explain the formation of many nonmembranous organelles. However, we know little about its ability to change in evolution. Here we studied the evolution of the mammalian RNA-binding protein Fused in Sarcoma (FUS), a protein whose prion-like domain (PLD) contributes t...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947763/ https://www.ncbi.nlm.nih.gov/pubmed/33022038 http://dx.doi.org/10.1093/molbev/msaa258 |