ABPP-HT - High-Throughput Activity-Based Profiling of Deubiquitylating Enzyme Inhibitors in a Cellular Context

The potency and selectivity of a small molecule inhibitor are key parameters to assess during the early stages of drug discovery. In particular, it is very informative for characterizing compounds in a relevant cellular context in order to reveal potential off-target effects and drug efficacy. Activ...

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Detalles Bibliográficos
Autores principales: Jones, Hannah B. L., Heilig, Raphael, Fischer, Roman, Kessler, Benedikt M., Pinto-Fernández, Adán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947856/
https://www.ncbi.nlm.nih.gov/pubmed/33718328
http://dx.doi.org/10.3389/fchem.2021.640105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947856/
https://www.ncbi.nlm.nih.gov/pubmed/33718328
http://dx.doi.org/10.3389/fchem.2021.640105

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