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In vitro Antibacterial Activity of an FDA-Approved H(+)-ATPase Inhibitor, Bedaquiline, Against Streptococcus mutans in Acidic Milieus

BACKGROUND: Dental caries is an acid-related disease. Current anti-caries agents mainly focus on the bacteriostatic effect in a neutral environment and do not target acid-resistant microorganisms related to caries in acidic milieus. OBJECTIVES: To assess the in vitro antibacterial activities of beda...

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Detalles Bibliográficos
Autores principales: Zhang, Meng, Yu, Wenqian, Zhou, Shujing, Zhang, Bing, Lo, Edward Chin Man, Xu, Xin, Zhang, Dongjiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947916/
https://www.ncbi.nlm.nih.gov/pubmed/33717046
http://dx.doi.org/10.3389/fmicb.2021.647611