Cardiolipin-mediated PPARγ S112 phosphorylation impairs IL-10 production and inflammation resolution during bacterial pneumonia

Bacterial pneumonia is a global healthcare burden, and unwarranted inflammation is suggested as an important cause of mortality. Optimum levels of the anti-inflammatory cytokine IL-10 are essential to reduce inflammation and improve survival in pneumonia. Elevated levels of the mitochondrial-DAMP ca...

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Detalles Bibliográficos
Autores principales: Garg, Mayank, Johri, Saumya, Sagar, Shakti, Mundhada, Aniruddha, Agrawal, Anurag, Ray, Prabir, Chakraborty, Krishnendu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947928/
https://www.ncbi.nlm.nih.gov/pubmed/33567272
http://dx.doi.org/10.1016/j.celrep.2021.108736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947928/
https://www.ncbi.nlm.nih.gov/pubmed/33567272
http://dx.doi.org/10.1016/j.celrep.2021.108736

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