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Deletion of the RGD motif in LON-2/glypican is associated with morphological abnormalities

The lon-2 gene in Caenorhabditis elegans encodes a heparan sulfate proteoglycan family glypican that negatively regulates the BMP signaling pathway responsible for controlling body length. LON-2 contains multiple functional domains, including an RGD (Arg-Gly-Asp) motif at amino acid number from 348...

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Detalles Bibliográficos
Autores principales: Park, Aileen, Qiu, Zhongqiang, Lee, Myeongwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948029/
https://www.ncbi.nlm.nih.gov/pubmed/33718824
http://dx.doi.org/10.17912/micropub.biology.000376