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Deletion of the RGD motif in LON-2/glypican is associated with morphological abnormalities
The lon-2 gene in Caenorhabditis elegans encodes a heparan sulfate proteoglycan family glypican that negatively regulates the BMP signaling pathway responsible for controlling body length. LON-2 contains multiple functional domains, including an RGD (Arg-Gly-Asp) motif at amino acid number from 348...
Autores principales: | Park, Aileen, Qiu, Zhongqiang, Lee, Myeongwoo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Caltech Library
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948029/ https://www.ncbi.nlm.nih.gov/pubmed/33718824 http://dx.doi.org/10.17912/micropub.biology.000376 |
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