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Location-specific cell identity rather than exposure to GI microbiota defines many innate immune signalling cascades in the gut epithelium

OBJECTIVE: The epithelial layer of the GI tract is equipped with innate immune receptors to sense invading pathogens. Dysregulation in innate immune signalling pathways is associated with severe inflammatory diseases, but the responsiveness of GI epithelial cells to bacterial stimulation remains unc...

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Detalles Bibliográficos
Autores principales: Kayisoglu, Ozge, Weiss, Franziska, Niklas, Carolin, Pierotti, Isabella, Pompaiah, Malvika, Wallaschek, Nina, Germer, Christoph-Thomas, Wiegering, Armin, Bartfeld, Sina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948175/
https://www.ncbi.nlm.nih.gov/pubmed/32571970
http://dx.doi.org/10.1136/gutjnl-2019-319919