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Location-specific cell identity rather than exposure to GI microbiota defines many innate immune signalling cascades in the gut epithelium
OBJECTIVE: The epithelial layer of the GI tract is equipped with innate immune receptors to sense invading pathogens. Dysregulation in innate immune signalling pathways is associated with severe inflammatory diseases, but the responsiveness of GI epithelial cells to bacterial stimulation remains unc...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948175/ https://www.ncbi.nlm.nih.gov/pubmed/32571970 http://dx.doi.org/10.1136/gutjnl-2019-319919 |