Cargando…

Location-specific cell identity rather than exposure to GI microbiota defines many innate immune signalling cascades in the gut epithelium

OBJECTIVE: The epithelial layer of the GI tract is equipped with innate immune receptors to sense invading pathogens. Dysregulation in innate immune signalling pathways is associated with severe inflammatory diseases, but the responsiveness of GI epithelial cells to bacterial stimulation remains unc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kayisoglu, Ozge, Weiss, Franziska, Niklas, Carolin, Pierotti, Isabella, Pompaiah, Malvika, Wallaschek, Nina, Germer, Christoph-Thomas, Wiegering, Armin, Bartfeld, Sina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Gut Microbiota
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948175/ https://www.ncbi.nlm.nih.gov/pubmed/32571970 http://dx.doi.org/10.1136/gutjnl-2019-319919

Ejemplares similares

Gut microbiota disturbance during antibiotic therapy: a multi-omic approach
por: Pérez-Cobas, Ana Elena, et al.
Publicado: (2013)

Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota
por: Serino, Matteo, et al.
Publicado: (2011)

Analysis of gut microbial regulation of host gene expression along the length of the gut and regulation of gut microbial ecology through MyD88
por: Larsson, Erik, et al.
Publicado: (2011)

Anal gas evacuation and colonic microbiota in patients with flatulence: effect of diet
por: Manichanh, Chaysavanh, et al.
Publicado: (2014)

Stool consistency is strongly associated with gut microbiota richness and composition, enterotypes and bacterial growth rates
por: Vandeputte, Doris, et al.
Publicado: (2016)

Commensal bacteria drive endogenous transformation and tumour stem cell marker expression through a bystander effect
por: Wang, Xingmin, et al.
Publicado: (2015)

Faecal microbiota transplantation: applications and limitations in treating gastrointestinal disorders
por: Sbahi, Hani, et al.
Publicado: (2016)

Proton pump inhibitors affect the gut microbiome
por: Imhann, Floris, et al.
Publicado: (2016)

Proton pump inhibitors alter the composition of the gut microbiota
por: Jackson, Matthew A, et al.
Publicado: (2016)

The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia
por: Schuijt, Tim J, et al.
Publicado: (2016)

Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults
por: Chambers, Edward S, et al.
Publicado: (2015)

Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence
por: Schaubeck, Monika, et al.
Publicado: (2016)

Spatial variation of the colonic microbiota in patients with ulcerative colitis and control volunteers
por: Lavelle, A, et al.
Publicado: (2015)

Primary sclerosing cholangitis is characterised by intestinal dysbiosis independent from IBD
por: Sabino, João, et al.
Publicado: (2016)

Bacteriophage transfer during faecal microbiota transplantation in Clostridium difficile infection is associated with treatment outcome
por: Zuo, Tao, et al.
Publicado: (2018)

Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction
por: Catry, Emilie, et al.
Publicado: (2018)

Gut symbiotic microbes imprint intestinal immune cells with the innate receptor SLAMF4 which contributes to gut immune protection against enteric pathogens
por: Cabinian, Allison, et al.
Publicado: (2018)

Changes in the gut microbiota composition and the plasma ghrelin level in patients with Helicobacter pylori-infected patients with eradication therapy
por: Yanagi, Hidetaka, et al.
Publicado: (2017)

Prebiotic inulin-type fructans induce specific changes in the human gut microbiota
por: Vandeputte, Doris, et al.
Publicado: (2017)

Dysbiosis of maternal and neonatal microbiota associated with gestational diabetes mellitus
por: Wang, Jinfeng, et al.
Publicado: (2018)

International Cancer Microbiome Consortium consensus statement on the role of the human microbiome in carcinogenesis
por: Scott, Alasdair J, et al.
Publicado: (2019)

Identification of TMAO-producer phenotype and host–diet–gut dysbiosis by carnitine challenge test in human and germ-free mice
por: Wu, Wei-Kai, et al.
Publicado: (2019)

Dietary supplementation with inulin-propionate ester or inulin improves insulin sensitivity in adults with overweight and obesity with distinct effects on the gut microbiota, plasma metabolome and systemic inflammatory responses: a randomised cross-over trial
por: Chambers, Edward S, et al.
Publicado: (2019)

Population-level analysis of Blastocystis subtype prevalence and variation in the human gut microbiota
por: Tito, Raul Y, et al.
Publicado: (2019)

Gut mucosal virome alterations in ulcerative colitis
por: Zuo, Tao, et al.
Publicado: (2019)

Gut microbiome analysis as a tool towards targeted non-invasive biomarkers for early hepatocellular carcinoma
por: Ren, Zhigang, et al.
Publicado: (2019)

Enteric fungal microbiota dysbiosis and ecological alterations in colorectal cancer
por: Coker, Olabisi Oluwabukola, et al.
Publicado: (2019)

The oral microbiota in colorectal cancer is distinctive and predictive
por: Flemer, Burkhardt, et al.
Publicado: (2018)

Periodontitis induced by Porphyromonas gingivalis drives periodontal microbiota dysbiosis and insulin resistance via an impaired adaptive immune response
por: Blasco-Baque, Vincent, et al.
Publicado: (2017)

Microbiota-induced obesity requires farnesoid X receptor
por: Parséus, Ava, et al.
Publicado: (2017)

Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism
por: Duparc, Thibaut, et al.
Publicado: (2017)

Tumour-associated and non-tumour-associated microbiota in colorectal cancer
por: Flemer, Burkhardt, et al.
Publicado: (2017)

Structural robustness of the gut mucosal microbiota is associated with Crohn's disease remission after surgery
por: Mondot, S, et al.
Publicado: (2016)

Intestinal microbiota is altered in patients with colon cancer and modified by probiotic intervention
por: Hibberd, Ashley A, et al.
Publicado: (2017)

Impairment of spermatogenesis and sperm motility by the high-fat diet-induced dysbiosis of gut microbes
por: Ding, Ning, et al.
Publicado: (2020)

Effect of Helicobacter pylori on gastrointestinal microbiota: a population-based study in Linqu, a high-risk area of gastric cancer
por: Guo, Yang, et al.
Publicado: (2020)

A purified membrane protein from Akkermansia muciniphila or the pasteurised bacterium blunts colitis associated tumourigenesis by modulation of CD8(+) T cells in mice
por: Wang, Lijuan, et al.
Publicado: (2020)

Discovery of the gut microbial signature driving the efficacy of prebiotic intervention in obese patients
por: Rodriguez, Julie, et al.
Publicado: (2020)

Acute appendicitis is associated with appendiceal microbiome changes including elevated Campylobacter jejuni levels
por: Oh, Sun Jung, et al.
Publicado: (2020)

Longitudinal metabolic and gut bacterial profiling of pregnant women with previous bariatric surgery
por: West, Kiana Ashley, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_n5vlh633od3bbeofp5fr9jnlad