Cargando…

Synthesis and Operating Optimization of the PEG Conjugate via CuAAC in scCO(2)

[Image: see text] A new sustainable green protocol for obtaining polyethylene glycol (PEG) conjugates, with a prototype molecule, which in this work was coumarin, by means of click chemistry is presented. The organic solvents commonly used for this type of reaction were replaced by supercritical car...

Descripción completa

Detalles Bibliográficos
Autores principales: López, Sonia, Gracia, Ignacio, García, María Teresa, Rodríguez, Juan Francisco, Ramos, María Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948234/
https://www.ncbi.nlm.nih.gov/pubmed/33718707
http://dx.doi.org/10.1021/acsomega.0c05466