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Synthesis and Operating Optimization of the PEG Conjugate via CuAAC in scCO(2)
[Image: see text] A new sustainable green protocol for obtaining polyethylene glycol (PEG) conjugates, with a prototype molecule, which in this work was coumarin, by means of click chemistry is presented. The organic solvents commonly used for this type of reaction were replaced by supercritical car...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948234/ https://www.ncbi.nlm.nih.gov/pubmed/33718707 http://dx.doi.org/10.1021/acsomega.0c05466 |