Association of NAT2 genetic polymorphism with the efficacy of Neurotropin® for the enhancement of aggrecan gene expression in nucleus pulposus cells: a pilot study

BACKGROUND: Intervertebral disc degeneration, one of the major causes of low-back pain, results from altered biosynthesis/turnover of extracellular matrix in the disc. Previously, we reported that the analgesic drug Neurotropin® (NTP) had an anabolic effect on glycosaminoglycan synthesis in cultured...

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Detalles Bibliográficos
Autores principales: Nakai, Tomoko, Sakai, Daisuke, Nakamura, Yoshihiko, Horikita, Natsumi, Matsushita, Erika, Naiki, Mitsuru, Watanabe, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948325/
https://www.ncbi.nlm.nih.gov/pubmed/33706752
http://dx.doi.org/10.1186/s12920-021-00926-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948325/
https://www.ncbi.nlm.nih.gov/pubmed/33706752
http://dx.doi.org/10.1186/s12920-021-00926-x

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