Endophilin recruitment drives membrane curvature generation through coincidence detection of GPCR loop interactions and negative lipid charge

Endophilin plays key roles during endocytosis of cellular receptors, including generating membrane curvature to drive internalization. Electrostatic interactions between endophilin’s BIN/Amphiphysin/Rvs domain and anionic membrane lipids have been considered the major driving force in curvature gene...

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Detalles Bibliográficos
Autores principales: Mondal, Samsuzzoha, Narayan, Karthik B., Powers, Imania, Botterbusch, Samuel, Baumgart, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948419/
https://www.ncbi.nlm.nih.gov/pubmed/33268381
http://dx.doi.org/10.1074/jbc.RA120.016118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948419/
https://www.ncbi.nlm.nih.gov/pubmed/33268381
http://dx.doi.org/10.1074/jbc.RA120.016118

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