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Endophilin recruitment drives membrane curvature generation through coincidence detection of GPCR loop interactions and negative lipid charge
Endophilin plays key roles during endocytosis of cellular receptors, including generating membrane curvature to drive internalization. Electrostatic interactions between endophilin’s BIN/Amphiphysin/Rvs domain and anionic membrane lipids have been considered the major driving force in curvature gene...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948419/ https://www.ncbi.nlm.nih.gov/pubmed/33268381 http://dx.doi.org/10.1074/jbc.RA120.016118 |