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USP13 interacts with cohesin and regulates its ubiquitination in human cells

Cohesin is a multiprotein ring complex that regulates 3D genome organization, sister chromatid cohesion, gene expression, and DNA repair. Cohesin is known to be ubiquitinated, although the mechanism, regulation, and effects of cohesin ubiquitination remain poorly defined. We previously used gene edi...

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Detalles Bibliográficos
Autores principales: He, Xiaoyuan, Kim, Jung-Sik, Diaz-Martinez, Laura A., Han, Cecil, Lane, William S., Budnik, Bogdan, Waldman, Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948425/
https://www.ncbi.nlm.nih.gov/pubmed/33334891
http://dx.doi.org/10.1074/jbc.RA120.015762