Cargando…

Physicochemical Profiling and Comparison of Research Antiplasmodials and Advanced Stage Antimalarials with Oral Drugs

[Image: see text] To understand the property space of antimalarials, we collated a large dataset of research antiplasmodial (RAP) molecules with known in vitro potencies and advanced stage antimalarials (ASAMs) with established oral bioavailability. While RAP molecules are “non-druglike”, ASAM molec...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhanot, Amritansh, Sundriyal, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948433/
https://www.ncbi.nlm.nih.gov/pubmed/33718733
http://dx.doi.org/10.1021/acsomega.1c00104