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Frameworks for targeting RNA with small molecules

Since the characterization of mRNA in 1961, our understanding of the roles of RNA molecules has significantly grown. Beyond serving as a link between DNA and proteins, RNA molecules play direct effector roles by binding to various ligands, including proteins, DNA, other RNAs, and metabolites. Throug...

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Detalles Bibliográficos
Autores principales: Umuhire Juru, Aline, Hargrove, Amanda E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948454/
https://www.ncbi.nlm.nih.gov/pubmed/33334887
http://dx.doi.org/10.1074/jbc.REV120.015203