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The role of cysteines in the structure and function of OGG1

8-Oxoguanine glycosylase (OGG1) is a base excision repair enzyme responsible for the recognition and removal of 8-oxoguanine, a commonly occurring oxidized DNA modification. OGG1 prevents the accumulation of mutations and regulates the transcription of various oxidative stress–response genes. In add...

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Detalles Bibliográficos
Autores principales: Wang, Katarina, Maayah, Marah, Sweasy, Joann B., Alnajjar, Khadijeh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948458/
https://www.ncbi.nlm.nih.gov/pubmed/33203705
http://dx.doi.org/10.1074/jbc.RA120.016126