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Volatile allosteric antagonists of mosquito odorant receptors inhibit human-host attraction

Odorant-dependent behaviors in insects are triggered by the binding of odorant ligands to the variable subunits of heteromeric olfactory receptors. Previous studies have shown, however, that specific odor binding to ORco, the common subunit of odorant receptor heteromers, may allosterically alter ol...

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Detalles Bibliográficos
Autores principales: Kythreoti, Georgia, Sdralia, Nadia, Tsitoura, Panagiota, Papachristos, Dimitrios P., Michaelakis, Antonios, Karras, Vasileios, Ruel, David M., Yakir, Esther, Bohbot, Jonathan D., Schulz, Stefan, Iatrou, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948460/
https://www.ncbi.nlm.nih.gov/pubmed/33298524
http://dx.doi.org/10.1074/jbc.RA120.016557