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ppGalNAc-T4-catalyzed O-Glycosylation of TGF-β type Ⅱ receptor regulates breast cancer cells metastasis potential

GalNAc-type O-glycosylation, initially catalyzed by polypeptide N-acetylgalactosaminyltransferases (ppGalNAc-Ts), is one of the most abundant and complex posttranslational modifications of proteins. Emerging evidence has proven that aberrant ppGalNAc-Ts are involved in malignant tumor transformation...

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Detalles Bibliográficos
Autores principales: Wu, Qiong, Zhang, Cheng, Zhang, Keren, Chen, Qiushi, Wu, Sijin, Huang, Huang, Huang, Tianmiao, Zhang, Nana, Wang, Xue, Li, Wenli, Liu, Yubo, Zhang, Jianing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948473/
https://www.ncbi.nlm.nih.gov/pubmed/33234595
http://dx.doi.org/10.1074/jbc.RA120.016345