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CCR3 deficiency is associated with increased osteoclast activity and reduced cortical bone volume in adult male mice

Increasing evidence emphasizes the importance of chemokines and chemokine receptors as regulators of bone remodeling. The C–C chemokine receptor 3 (CCR3) is dramatically upregulated during osteoclastogenesis, but the role of CCR3 in osteoclast formation and bone remodeling in adult mice is unknown....

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Detalles Bibliográficos
Autores principales: Rosendahl, Sara, Sulniute, Rima, Eklund, Michaela, Koskinen Holm, Cecilia, Johansson, Marcus J.O., Kindstedt, Elin, Lindquist, Susanne, Lundberg, Pernilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948475/
https://www.ncbi.nlm.nih.gov/pubmed/33303631
http://dx.doi.org/10.1074/jbc.RA120.015571