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CCR3 deficiency is associated with increased osteoclast activity and reduced cortical bone volume in adult male mice
Increasing evidence emphasizes the importance of chemokines and chemokine receptors as regulators of bone remodeling. The C–C chemokine receptor 3 (CCR3) is dramatically upregulated during osteoclastogenesis, but the role of CCR3 in osteoclast formation and bone remodeling in adult mice is unknown....
Autores principales: | Rosendahl, Sara, Sulniute, Rima, Eklund, Michaela, Koskinen Holm, Cecilia, Johansson, Marcus J.O., Kindstedt, Elin, Lindquist, Susanne, Lundberg, Pernilla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948475/ https://www.ncbi.nlm.nih.gov/pubmed/33303631 http://dx.doi.org/10.1074/jbc.RA120.015571 |
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