Ferroptosis drives photoreceptor degeneration in mice with defects in all-trans-retinal clearance

The death of photoreceptor cells in dry age-related macular degeneration (AMD) and autosomal recessive Stargardt disease (STGD1) is closely associated with disruption in all-trans-retinal (atRAL) clearance in neural retina. In this study, we reveal that the overload of atRAL leads to photoreceptor d...

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Detalles Bibliográficos
Autores principales: Chen, Chao, Chen, Jingmeng, Wang, Yan, Liu, Zuguo, Wu, Yalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948481/
https://www.ncbi.nlm.nih.gov/pubmed/33334878
http://dx.doi.org/10.1074/jbc.RA120.015779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948481/
https://www.ncbi.nlm.nih.gov/pubmed/33334878
http://dx.doi.org/10.1074/jbc.RA120.015779

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