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Erythrocytes efficiently utilize exogenous sphingosines for S1P synthesis and export via Mfsd2b

Sphingosine-1-phosphate (S1P) is a potent lipid mediator that exerts its activity via activation of five different G protein–coupled receptors, designated as S1P1–5. This potent lipid mediator is synthesized from the sphingosine precursor by two sphingosine kinases (SphK1 and 2) and must be exported...

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Detalles Bibliográficos
Autores principales: Nguyen, Toan Q., Vu, Thiet Minh, Tukijan, Farhana, Muralidharan, Sneha, Foo, Juat Chin, Li Chin, Jasmine Fei, Hasan, Zafrul, Torta, Federico, Nguyen, Long N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948482/
https://www.ncbi.nlm.nih.gov/pubmed/33334894
http://dx.doi.org/10.1074/jbc.RA120.012941