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Mössbauer and LC-ICP-MS investigation of iron trafficking between vacuoles and mitochondria in vma2ΔSaccharomyces cerevisiae

Vacuoles are acidic organelles that store Fe(III) polyphosphate, participate in iron homeostasis, and have been proposed to deliver iron to mitochondria for iron–sulfur cluster (ISC) and heme biosynthesis. Vma2Δ cells have dysfunctional V-ATPases, rendering their vacuoles nonacidic. These cells have...

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Detalles Bibliográficos
Autores principales: Kim, Joshua E., Vali, Shaik Waseem, Nguyen, Trang Q., Dancis, Andrew, Lindahl, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948489/
https://www.ncbi.nlm.nih.gov/pubmed/33268384
http://dx.doi.org/10.1074/jbc.RA120.015907