Histone demethylase JMJD2D promotes the self-renewal of liver cancer stem-like cells by enhancing EpCAM and Sox9 expression

Cancer stem-like cells (CSCs) contribute to the high rate of tumor heterogeneity, metastasis, therapeutic resistance, and recurrence. Histone lysine demethylase 4D (KDM4D or JMJD2D) is highly expressed in colon and liver tumors, where it promotes cancer progression; however, the role of JMJD2D in CS...

Descripción completa

Detalles Bibliográficos
Autores principales: Deng, Yuan, Li, Ming, Zhuo, Minghui, Guo, Peng, Chen, Qiang, Mo, Pingli, Li, Wengang, Yu, Chundong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948496/
https://www.ncbi.nlm.nih.gov/pubmed/33434575
http://dx.doi.org/10.1074/jbc.RA120.015335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948496/
https://www.ncbi.nlm.nih.gov/pubmed/33434575
http://dx.doi.org/10.1074/jbc.RA120.015335

Ejemplares similares