Optimization of a peptide ligand for the adhesion GPCR ADGRG2 provides a potent tool to explore receptor biology

The adhesion GPCR ADGRG2, also known as GPR64, is a critical regulator of male fertility that maintains ion/pH homeostasis and CFTR coupling. The molecular basis of ADGRG2 function is poorly understood, in part because no endogenous ligands for ADGRG2 have been reported, thus limiting the tools avai...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Yujing, Zhang, Daolai, Ma, Ming-Liang, Lin, Hui, Song, Youchen, Wang, Junyan, Ma, Chuanshun, Yu, Ke, An, Wentao, Guo, Shengchao, He, Dongfang, Yang, Zhao, Xiao, Peng, Hou, Guige, Yu, Xiao, Sun, Jin-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948503/
https://www.ncbi.nlm.nih.gov/pubmed/33303626
http://dx.doi.org/10.1074/jbc.RA120.014726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948503/
https://www.ncbi.nlm.nih.gov/pubmed/33303626
http://dx.doi.org/10.1074/jbc.RA120.014726

Ejemplares similares