Cargando…

MEKK2 and MEKK3 orchestrate multiple signals to regulate Hippo pathway

The Hippo pathway is an evolutionarily conserved signaling pathway that controls organ size in animals via the regulation of cell proliferation and apoptosis. It consists of a kinase cascade, in which MST1/2 and MAP4Ks phosphorylate and activate LATS1/2, which in turn phosphorylate and inhibit YAP/T...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Jinqiu, Hu, Zonghao, Deng, Yujie, Wu, Qingzhe, Wu, Ming, Song, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948509/
https://www.ncbi.nlm.nih.gov/pubmed/33571521
http://dx.doi.org/10.1016/j.jbc.2021.100400