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Ongoing replication forks delay the nuclear envelope breakdown upon mitotic entry

DNA replication is a major contributor to genomic instability, and protection against DNA replication perturbation is essential for normal cell division. Certain types of replication stress agents, such as aphidicolin and hydroxyurea, have been shown to cause reversible replication fork stalling, wh...

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Detalles Bibliográficos
Autores principales: Hashimoto, Yoshitami, Tanaka, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948514/
https://www.ncbi.nlm.nih.gov/pubmed/33148697
http://dx.doi.org/10.1074/jbc.RA120.015142