Respiratory FimA-Specific Secretory IgA Antibodies Upregulated by DC-Targeting Nasal Double DNA Adjuvant Are Essential for Elimination of Porphyromonas gingivalis

Our previous studies showed that a combination of a DNA plasmid encoding Flt3 ligand (pFL) and CpG oligodeoxynucleotides 1826 (CpG ODN) (FL/CpG) as a nasal adjuvant provoked antigen-specific immune responses. In this study, we investigated the efficacy of a nasal vaccine consisting of FimA as the st...

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Detalles Bibliográficos
Autores principales: Kataoka, Kosuke, Kawabata, Shigetada, Koyanagi, Kayo, Hashimoto, Yoshiya, Miyake, Tatsuro, Fujihashi, Kohtaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948520/
https://www.ncbi.nlm.nih.gov/pubmed/33717178
http://dx.doi.org/10.3389/fimmu.2021.634923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948520/
https://www.ncbi.nlm.nih.gov/pubmed/33717178
http://dx.doi.org/10.3389/fimmu.2021.634923

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