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The SARS-CoV-2 Y453F mink variant displays a pronounced increase in ACE-2 affinity but does not challenge antibody neutralization

Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 from humans to animals has been reported for many domesticated species, including farmed minks. The identification of novel spike gene mutations appearing in minks has raised major concerns about potential immune evasion and challenges...

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Detalles Bibliográficos
Autores principales: Bayarri-Olmos, Rafael, Rosbjerg, Anne, Johnsen, Laust Bruun, Helgstrand, Charlotte, Bak-Thomsen, Theresa, Garred, Peter, Skjoedt, Mikkel-Ole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948531/
https://www.ncbi.nlm.nih.gov/pubmed/33716040
http://dx.doi.org/10.1016/j.jbc.2021.100536