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Dysregulation of intercellular signaling by MOF deletion leads to liver injury

Epigenetic mechanisms that alter heritable gene expression and chromatin structure play an essential role in many biological processes, including liver function. Human MOF (males absent on the first) is a histone acetyltransferase that is globally downregulated in human steatohepatitis. However, the...

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Detalles Bibliográficos
Autores principales: Lei, Hongwei, denDekker, Aaron D., Li, Guobing, Zhang, Zhiguo, Sha, Liang, Schaller, Matthew A., Kunkel, Steven L., Rui, Liangyou, Tao, Kaixiong, Dou, Yali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948572/
https://www.ncbi.nlm.nih.gov/pubmed/33376138
http://dx.doi.org/10.1074/jbc.RA120.016079