Dynamic multimerization of Dab2–Myosin VI complexes regulates cargo processivity while minimizing cortical actin reorganization

Myosin VI ensembles on endocytic cargo facilitate directed transport through a dense cortical actin network. Myosin VI is recruited to clathrin-coated endosomes via the cargo adaptor Dab2. Canonically, it has been assumed that the interactions between a motor and its cargo adaptor are stable. Howeve...

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Detalles Bibliográficos
Autores principales: Rai, Ashim, Vang, Duha, Ritt, Michael, Sivaramakrishnan, Sivaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948593/
https://www.ncbi.nlm.nih.gov/pubmed/33372034
http://dx.doi.org/10.1074/jbc.RA120.012703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948593/
https://www.ncbi.nlm.nih.gov/pubmed/33372034
http://dx.doi.org/10.1074/jbc.RA120.012703

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