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Dynamic multimerization of Dab2–Myosin VI complexes regulates cargo processivity while minimizing cortical actin reorganization

Myosin VI ensembles on endocytic cargo facilitate directed transport through a dense cortical actin network. Myosin VI is recruited to clathrin-coated endosomes via the cargo adaptor Dab2. Canonically, it has been assumed that the interactions between a motor and its cargo adaptor are stable. Howeve...

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Detalles Bibliográficos
Autores principales:	Rai, Ashim, Vang, Duha, Ritt, Michael, Sivaramakrishnan, Sivaraj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948593/ https://www.ncbi.nlm.nih.gov/pubmed/33372034 http://dx.doi.org/10.1074/jbc.RA120.012703

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