1,6-Hexanediol, commonly used to dissolve liquid–liquid phase separated condensates, directly impairs kinase and phosphatase activities

The concept of liquid–liquid phase separation (LLPS) has emerged as an intriguing mechanism for the organization of membraneless compartments in cells. The alcohol 1,6-hexanediol is widely used as a control to dissolve LLPS assemblies in phase separation studies in diverse fields. However, little is...

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Detalles Bibliográficos
Autores principales: Düster, Robert, Kaltheuner, Ines H., Schmitz, Maximilian, Geyer, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948595/
https://www.ncbi.nlm.nih.gov/pubmed/33814344
http://dx.doi.org/10.1016/j.jbc.2021.100260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948595/
https://www.ncbi.nlm.nih.gov/pubmed/33814344
http://dx.doi.org/10.1016/j.jbc.2021.100260

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