A vicious cycle of bisretinoid formation and oxidation relevant to recessive Stargardt disease

The ability of iron to transfer electrons enables the contribution of this metal to a variety of cellular activities even as the redox properties of iron are also responsible for the generation of hydroxyl radicals ((•)OH), the most destructive of the reactive oxygen species. We previously showed th...

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Detalles Bibliográficos
Autores principales: Zhao, Jin, Kim, Hye Jin, Ueda, Keiko, Zhang, Kevin, Montenegro, Diego, Dunaief, Joshua L., Sparrow, Janet R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948646/
https://www.ncbi.nlm.nih.gov/pubmed/33837742
http://dx.doi.org/10.1016/j.jbc.2021.100259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948646/
https://www.ncbi.nlm.nih.gov/pubmed/33837742
http://dx.doi.org/10.1016/j.jbc.2021.100259

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