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Anti-GPR56 monoclonal antibody potentiates GPR56-mediated Src-Fak signaling to modulate cell adhesion

GPR56 is a member of the adhesion G-protein-coupled receptor family shown to play important roles in cell adhesion, brain development, immune function, and tumorigenesis. GPR56 is highly upregulated in colorectal cancer and correlates with poor prognosis. Several studies have shown GPR56 couples to...

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Detalles Bibliográficos
Autores principales: Chatterjee, Treena, Zhang, Sheng, Posey, Tressie A., Jacob, Joan, Wu, Ling, Yu, Wangsheng, Francisco, Liezl E., Liu, Qingyun J., Carmon, Kendra S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948743/
https://www.ncbi.nlm.nih.gov/pubmed/33837725
http://dx.doi.org/10.1016/j.jbc.2021.100261