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Piezo1 acts upstream of TRPV4 to induce pathological changes in endothelial cells due to shear stress
The ion channels Piezo1 and TRPV4 have both, independently, been implicated in high venous pressure– and fluid shear stress–induced vascular hyperpermeability in endothelial cells. However, the mechanism by which Piezo1 and TRPV4 channels execute the same function is poorly understood. Here we demon...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948745/ https://www.ncbi.nlm.nih.gov/pubmed/33298523 http://dx.doi.org/10.1074/jbc.RA120.015059 |