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A quantitative method to detect non-antithrombin-binding 3-O-sulfated units in heparan sulfate

Heparan sulfate is synthesized by most animal cells and interacts with numerous proteins via specific sulfation motifs to regulate various physiological processes. Various 3-O-sulfated motifs are considered to be key in controlling the binding specificities to the functional proteins. One such motif...

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Detalles Bibliográficos
Autores principales: Mochizuki, Hideo, Futatsumori, Hideyuki, Suzuki, Eriko, Kimata, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948761/
https://www.ncbi.nlm.nih.gov/pubmed/33234593
http://dx.doi.org/10.1074/jbc.RA120.015864