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Complement receptor 3 mediates both sinking phagocytosis and phagocytic cup formation via distinct mechanisms

A long-standing hypothesis is that complement receptors (CRs), especially CR3, mediate sinking phagocytosis, but evidence is lacking. Alternatively, CRs have been reported to induce membrane ruffles or phagocytic cups, akin to those induced by Fcγ receptors (FcγRs), but the details of these events a...

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Detalles Bibliográficos
Autores principales: Walbaum, Stefan, Ambrosy, Benjamin, Schütz, Paula, Bachg, Anne C., Horsthemke, Markus, Leusen, Jeanette H.W., Mócsai, Attila, Hanley, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948798/
https://www.ncbi.nlm.nih.gov/pubmed/33839682
http://dx.doi.org/10.1016/j.jbc.2021.100256