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Enzymatic characterization of three human RNA adenosine methyltransferases reveals diverse substrate affinities and reaction optima
RNA methylations of varied RNA species (mRNA, tRNA, rRNA, non-coding RNA) generate a range of modified nucleotides, including N6-methyladenosine. Here we study the enzymology of three human RNA methyltransferases that methylate the adenosine amino group in diverse contexts, when it is: the first tra...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948815/ https://www.ncbi.nlm.nih.gov/pubmed/33428944 http://dx.doi.org/10.1016/j.jbc.2021.100270 |