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Captopril reduces lung inflammation and accelerated senescence in response to thoracic radiation in mice

The lung is sensitive to radiation and exhibits several phases of injury, with an initial phase of radiation-induced pneumonitis followed by delayed and irreversible fibrosis. The angiotensin-converting enzyme inhibitor captopril has been demonstrated to mitigate radiation lung injury and to improve...

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Detalles Bibliográficos
Autores principales: Mungunsukh, Ognoon, George, Jeffy, McCart, Elizabeth A, Snow, Andrew L, Mattapallil, Joseph J, Mog, Steven R, Panganiban, Ronald Allan M, Bolduc, David L, Rittase, W Bradley, Bouten, Roxane M, Day, Regina M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948861/
https://www.ncbi.nlm.nih.gov/pubmed/33616187
http://dx.doi.org/10.1093/jrr/rraa142