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Captopril reduces lung inflammation and accelerated senescence in response to thoracic radiation in mice
The lung is sensitive to radiation and exhibits several phases of injury, with an initial phase of radiation-induced pneumonitis followed by delayed and irreversible fibrosis. The angiotensin-converting enzyme inhibitor captopril has been demonstrated to mitigate radiation lung injury and to improve...
Autores principales: | Mungunsukh, Ognoon, George, Jeffy, McCart, Elizabeth A, Snow, Andrew L, Mattapallil, Joseph J, Mog, Steven R, Panganiban, Ronald Allan M, Bolduc, David L, Rittase, W Bradley, Bouten, Roxane M, Day, Regina M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948861/ https://www.ncbi.nlm.nih.gov/pubmed/33616187 http://dx.doi.org/10.1093/jrr/rraa142 |
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