Disturbances in PP2A methylation and one-carbon metabolism compromise Fyn distribution, neuritogenesis, and APP regulation

The nonreceptor protein tyrosine kinase Fyn and protein Ser/Thr phosphatase 2A (PP2A) are major multifunctional signaling molecules. Deregulation of Fyn and altered PP2A methylation are implicated in cancer and Alzheimer's disease (AD). Here, we tested the hypothesis that the methylation state...

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Detalles Bibliográficos
Autores principales: Taleski, Goce, Schuhmacher, Diana, Su, Henry, Sontag, Jean-Marie, Sontag, Estelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948947/
https://www.ncbi.nlm.nih.gov/pubmed/33380425
http://dx.doi.org/10.1074/jbc.RA120.016069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948947/
https://www.ncbi.nlm.nih.gov/pubmed/33380425
http://dx.doi.org/10.1074/jbc.RA120.016069

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