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Defining the reducing system of the NO dioxygenase cytoglobin in vascular smooth muscle cells and its critical role in regulating cellular NO decay

In smooth muscle, cytoglobin (Cygb) functions as a potent nitric oxide (NO) dioxygenase and regulates NO metabolism and vascular tone. Major questions remain regarding which cellular reducing systems regulate Cygb-mediated NO metabolism. To better define the Cygb-mediated NO dioxygenation process in...

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Detalles Bibliográficos
Autores principales: Ilangovan, Govindasamy, Khaleel, Sahar A., Kundu, Tapan, Hemann, Craig, El-Mahdy, Mohamed A., Zweier, Jay L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948950/
https://www.ncbi.nlm.nih.gov/pubmed/33334890
http://dx.doi.org/10.1074/jbc.RA120.016394