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The ATPase mechanism of myosin 15, the molecular motor mutated in DFNB3 human deafness
Cochlear hair cells each possess an exquisite bundle of actin-based stereocilia that detect sound. Unconventional myosin 15 (MYO15) traffics and delivers critical molecules required for stereocilia development and thus is essential for building the mechanosensory hair bundle. Mutations in the human...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948958/ https://www.ncbi.nlm.nih.gov/pubmed/33372036 http://dx.doi.org/10.1074/jbc.RA120.014903 |