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1α,25-Dihydroxyvitamin D3 ameliorates diabetes-induced bone loss by attenuating FoxO1-mediated autophagy

Autophagy is vital for maintaining cellular homeostasis through removing impaired organelles. It has recently been found to play pivotal roles in diabetes mellitus (DM), which is associated with increased bone fracture risk and loss of bone density. However, the mechanism whereby autophagy modulates...

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Detalles Bibliográficos
Autores principales: Jiang, Yixuan, Luo, Wenqiong, Wang, Bin, Yi, Zumu, Gong, Ping, Xiong, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948959/
https://www.ncbi.nlm.nih.gov/pubmed/33450223
http://dx.doi.org/10.1016/j.jbc.2021.100287