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Synaptophysin controls synaptobrevin-II retrieval via a cryptic C-terminal interaction site

The accurate retrieval of synaptic vesicle (SV) proteins during endocytosis is essential for the maintenance of neurotransmission. Synaptophysin (Syp) and synaptobrevin-II (SybII) are the most abundant proteins on SVs. Neurons lacking Syp display defects in the activity-dependent retrieval of SybII...

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Detalles Bibliográficos
Autores principales: Harper, Callista B., Blumrich, Eva-Maria, Cousin, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948965/
https://www.ncbi.nlm.nih.gov/pubmed/33769286
http://dx.doi.org/10.1016/j.jbc.2021.100266