Heme oxygenase-1 affects cytochrome P450 function through the formation of heteromeric complexes: Interactions between CYP1A2 and heme oxygenase-1

Heme oxygenase 1 (HO-1) and the cytochromes P450 (P450s) are endoplasmic reticulum–bound enzymes that rely on the same protein, NADPH-cytochrome P450 reductase (POR), to provide the electrons necessary for substrate metabolism. Although the HO-1 and P450 systems are interconnected owing to their com...

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Detalles Bibliográficos
Autores principales: Connick, J. Patrick, Reed, James R., Cawley, George F., Backes, Wayne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948974/
https://www.ncbi.nlm.nih.gov/pubmed/33148696
http://dx.doi.org/10.1074/jbc.RA120.015911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948974/
https://www.ncbi.nlm.nih.gov/pubmed/33148696
http://dx.doi.org/10.1074/jbc.RA120.015911

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